PORTO CANCER MEETING
PREVIOUS EDITIONS
26th PORTO CANCER MEETING 2019
PORTO CANCER MEETING 2019 | MENU
Program
PROGRAMME PORTO-BORDEAUX MEETING
01 MAY 2019
8.15 Registration
Opening Session
8.45 Welcome Session
Béatrice Vergier, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Jean-Philippe Merlio, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Manuel Sobrinho Simões, i3S/IPATIMUP & Faculty of Medicine of the University of Porto & CHUSJ
Rui Henrique, Portuguese Oncology Institute of Porto & ICBAS
Session I – The Cancer Ecosystem: applications in pathology
Chairs: Fátima Carneiro and Jean-Philippe Merlio
9.00 Tumour infiltrating lymphocytes and PD-L1 in breast carcinomas
Fernando Schmitt
9.20 Clinical, histological and molecular predictors of metastatic melanoma responses to anti-PD-1 immunotherapy
M. Darmon and B. Vergier
9.40 Impact of STK11/LKB1 tumour suppressor gene mutations on the response of bronchopulmonary carcinomas to immunotherapy
H. Bégueret and D. Cappelen
10.00 The microbiome and gastric cancer: beyond Helicobacter pylori
Céu Figueiredo
10:20 Coffee break
Session II – The Cancer Ecosystem: perspectives in pathology research
Chairs: Leonor David and David Cappelen
10:40 DICER1 germline alterations in papillary thyroid carcinoma cases from TCGA database
Sule Canberk
11:00 Proteomic profiling of liver CK7+/CK20- (A)DKs on FFPE blocks: primary versus metastatic?
C. Laffon, A.A. Raymond and B. Le Bail
11:20 The “genvironment” and the major role of epigenetics in human germ cell tumours: looking for disease biomarkers and novel treatment options
João Lobo
11:40 Uterine and vaginal sarcomas resembling fibrosarcoma: a clinicopathological and molecular analysis of 13 cases showing common NTRK-rearrangements and the description of a COL1A1-PDGFB fusion novel to uterine neoplasms
S. Croce
Session III – Hot topics in pathology: Battle of controversies
Chairs: Catarina Eloy and Brigitte Le-Bail
12:00Is p16 a decisive surrogate marker to diagnose HPV related carcinomas?
Con: Carla Bartosch
Pros: José Manuel Lopes
12:25Is NGS necessary to assess mutations (or is FISH still necessary)?
Con: José Carlos Machado
Pros: Jean-Philippe Merlio
12:50 Lunch break + Group Photo
Session IV – Interactive Cyto-histologic Slide Seminar – Part I
Chairs: Manuel Sobrinho Simões and Béatrice Vergier
15:00 Coffee break
Session IV – Interactive Cyto-histologic Slide Seminar – Part II
Chairs: Mariana Afonso and Sabrina Croce
Organizing Committee
Bordeaux Team
BELLEANNÉE Geneviève, CHU Bordeaux
CAPPELLEN David, CHU and Inserm U1053
CROCE Sabrina, Bergonié Institute and Inserm U1218
LE-BAIL Brigitte, CHU Bordeaux and Inserm U1053
MERLIO Jean-Philippe, CHU Bordeaux and Inserm U1053
VERGIER Béatrice, CHU Bordeaux and Inserm U1053
Porto Team
Manuel Sobrinho Simões, i3S/IPATIMUP & CHUSJ & FMUP
Fátima Carneiro, i3S/IPATIMUP & CHUSJ & FMUP
Carla Bartosch, IPO & ICBAS
Elisabete Rios, i3S/IPATIMUP & CHUSJ & FMUP
António Polónia, i3S/IPATIMUP
Catarina Costa, CHUSJ & FMUP
Tiago Costa Pereira, CHUSJ
26th Porto Cancer Meeting 2019
The Cancer Ecosystem: From Research to Pathology and Treatment
& 5th Joint Meeting Porto-Bordeaux 2019
02 MAY 2019
09.00 Welcome Session, Manuel Sobrinho-Simões, i3S/ Ipatimup & Mário Barbosa, i3S
Session 1: Microbiome in Cancer
Chairs: Fátima Carneiro, CHSJ and Céu Figueiredo, i3S
9.15-9.45 Role of the gut microbiome in causing, detecting and treating colorectal cancer
Paul O’Toole, School of Microbiology, University College Cork, Ireland
9.45-10.15 Interplay between immune contexture and gut microbiota in human colorectal cancer
Giandomenica Iezzi, Ente Ospedaliero Cantonale and Università della Svizzera Italiana, Switzerland
10.15-10.45 Coffee-break
10.45-11.15 Gut microbiota, can we improve the outcome of cancer immunotherapy
Meriem Messaoudene, Centre de Recherche du Centre Hospitalier de l’Universite de Montreal, Canada
11.15-11.30 SELECTED TALK: Gastric cancer is characterized by a dysbiotic microbiome
Rui Ferreira, i3S – Instituto de Investigação e Inovação em Saúde/ Ipatimup, Portugal
SPECIAL SESSION: A tribute to society
Chair: José Carlos Machado, i3S
11.30-12.00 How the contributions from society have improved the clinical management and molecular understanding of paediatric brain tumours
Jorge Lima, i3S – Instituto de Investigação e Inovação em Saúde, Portugal
Maria João Gil da Costa, Department of Paediatric Oncology, Centro Hospitalar de São João, Portugal
12.00-13.00 Lunch
13.00-14.30 Speed Talks | Auditorium Corino de Andrade
Chairs: Patrícia Oliveira, i3S and Hugo Caires, i3S
Session 2: Tumour Microenvironment
Chairs: Rui Henrique, IPO-Porto and Raquel Seruca, i3S
14.30-15.00 The crosstalk between stem-like cancer cells and the tumor microenvironment
Joana Paredes, i3S – Instituto de Inovação em Saúde / Ipatimup, Portugal
15.00-15.30 Metabolic interactions in chronic lymphocytic leukemia
Dimitrios Mougiakakos, Department of Medicine 5 – Hematology and Clinical Oncology, University of Erlangen, Germany
15.30-16.00 Coffee-break
16.00-16.30 Neoadjuvant chemotherapy elicits a pro-metastatic cascade through extracellular vesicles
Ioanna Keklikoglou, Swiss Institute for Experimental Cancer Research, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Switzerland
16.30-16.45 SELECTED TALK: Pancreatic Cancer Stem Cells Coordinate an Organized Exosomes Communication Network that Dysregulates the Hippo Pathway Contributing to Pancreatic Cancer Progression
Carolina Ruivo, i3S – Instituto de Investigação e Inovação em Saúde and Instituto de Ciências Biomédicas de Abel Salazar, Portugal
20.00 Meeting Dinner
03 MAY 2019
Session 3: Inflammation and Cancer
Chairs: Guilherme Macedo, CHSJ and José Carlos Machado, i3S
9.00-9.30 “Inflammation and homeostasis” to understand “Inflammation and cancer”
Francisco Real, Spanish National Cancer Research Centre / Universitat Pompeu Fabra, Spain
09.30-10.00Immune-metabolism in Liver Cancer and Cancer Cachexia
Erwin Wagner, Medical University Vienna, Austria
10.00-10.30 Coffee Break
10.30-11.00 On the role of innate and adaptive immune cells in fatty liver disease and subsequent liver cancer
Mathias Heikenwälder, Chronic Inflammation and Cancer, German Cancer Research Center, Heidelberg, Germany
11.00-11.15 SELECTED TALK: Crosstalk of signaling hubs and chronic inflammation in human tumorigenesis
Carla Lopes, Instituto Gulbenkian de Ciência, Portugal
11.15-12.30 Speed Talks | Auditorium Corino de Andrade
Chairs: Sérgia Velho, i3S and Stefan Mereiter, i3S
12.30-14.00 Lunch and Poster viewing
Session 4: Immunotherapy
Chairs: Júlio Oliveira, IPO-Porto and Sónia Melo, i3S
Suppression and Tumor Progression
Wei Guo, Department of Biology, School of Arts & Sciences, University of Pennsylvania, USA
14.30-15.00 Neoadjuvant immunotherapy – the pathway to biomarker identification and personalized therapy
Christian Blank, Netherlands Cancer Institute, the Netherlands
15.00-15.30 Coffee-break
16.00-16.30 Signal Finding Platform trials: optimizing drug development
Pablo Martinez Rodriguez, Medimmune, LLC, USA
16.30-16.45 SELECTED TALK: Homologous recombination deficiency in metastatic gastric cancer
Nuno Sousa, IPO-Porto, Portugal
Adjourn
