24th Porto Cancer Meeting 2017

Liquid biopsy: bringing precision medicine closer to oncology

11 May 2017

09:00 Welcome Session
Manuel Sobrinho-Simões, i3S – Ipatimup, Mário Barbosa, i3S 

Session 1: Liquid biopsies: the basics

Chairs: Raquel Seruca (i3S-Ipatimup) and Carmen Jerónimo (IPO-Porto)

09:30 Liquid biopsies: our path from bench to clinical management of cancer patients
José Luís Costa, i3S – Ipatimup

10:00 Structures, origins and functions of circulating DNA and move towards application in oncology
Alain R. Thierry
, Inserm, Université des Sciences de Montpellier, France

10:30 Coffee break

Chairs: Rui Henrique (IPO-Porto) and José Luís Costa (i3S-Ipatimup)

11:00 Exploiting the Biology of Exosomes for Diagnosis and Treatment of Pancreatic Cancer
Raghu Kalluri, The University of Texas MD Anderson Cancer Center, USA

11:30 The use of circulating tumor cells (CTC) as a liquid biopsy tool in cancer research
Harriet Wikman, Institute of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany

12:30 Lunch (lobby of Corino de Andrade Auditorium)

13:45 Posters Speed-talks Session (1st Floor – Room A)

Session 2: Technology for liquid biopsies

Chairs: José Carlos Machado (i3S-Ipatimup) and Fernando Schmitt (i3S-Ipatimup)

15:00 Droplet-based digital PCR for cancer research
Valerie Taly
, CNRS Research Director / Université Paris Descartes, France

15:30 Cancer Biomarker Detection
Goreti Sales, 
BioMark, Sensor Research ISEP, Porto, Portugal

16:00 Coffee break

Session 3: Liquid Biopsy: the perspective from the health industry

Chairs: Júlio Oliveira (IPO-Porto) and André Albergaria (i3S-Ipatimup)

16:30 DNA Sequencing of Clinical Plasma Samples to Identify Markers of Response and Resistance in Cancer Patients
Brian Dougherty,
AstraZeneca Oncology IMED Translational Science Group, USA

17:00 Developments in tools for Oncology testing from Ion Torrent
Andy Felton, ThermoFisher, USA

20:00 Meeting Dinner: Cruise on the Douro river and dinner aboard.

12 May 2017

Session 4:  Liquid biopsies clinical applications

Chairs: Venceslau Hespanhol (Centro Hospitalar de S. João) and Luís Costa (Lisbon University, Hospital de Santa Maria)

09:00 AR-V7 as a biomarker and therapeutic target for advanced prostate cancer
Emmanuel Antonarakis
, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, USA

09:30 Cancer evolution as a therapeutic target
Alberto Bardelli
, Candiolo Cancer Institute IRCCS / University of Torino, Italy

10:00 Coffee break

Chairs: Fátima Carneiro (Centro Hospitalar de S. João) and Nuno Sousa (IPO-Porto)

10:30 Liquid Biopsies in Clinical Oncology: how many dimensions and how much dynamics?
Luís Costa
, Lisbon University / Hospital de Santa Maria, Portugal

11:00 EGFR plasma testing in Lung Cancer –  practical experience
Shobhit Baijal,
Heartlands Hospital Birmingham, UK / Phillipe Taniere, Queen Elizabeth Hospital / Birmingham Medical School, UK

12:00 Lunch (lobby of Corino de Andrade Auditorium)

13:45 Posters Speed-talks Session (1st Floor – Room A)

Session 5: Implementation of liquid biopsies for precision medicine

Chairs: Celso Reis (i3S-Ipatimup) and Ana Castro (Centro Hospitalar do Porto)

15:00 New Horizons for Improvements in outcome or patients with Small Cell Lung Cancer
Caroline Dive
, Cancer Research UK Manchester Institute, UK

15:30 From Research to Routine: a snapshot into the clinical use of Liquid Biopsy in Molecular Diagnostics
Luca Quagliata
, Universitätsspital Basel, Switzerland

16:00 Closing