Program
LISBON TIME – WEST TIME
11 May 2023
12 May 2023
9:00 – 9:20 Welcome Session
Manuel Sobrinho-Simões, Claudio Sunkel and Celso Reis
Session 1: Glycosylation in Cancer
Chairs: Fátima Carneiro (CHSJ/FMUP/i3S) & Henrique Duarte (i3S)
9:20 – 9:50 Overview of glycosylation in gastrointestinal cancer and clinical implications
Celso Reis, IPATIMUP/i3S University of Porto, Portugal.
KEYNOTE TALK
9:50 – 10:30 Glycosylation-dependent mechanisms that regulate neoplastic transformation
Susan Bellis, Comprehensive Cancer Center, University of Alabama, USA
10:30-11:00 Coffee break
KEYNOTE TALK
Chairs: Catarina Gomes (i3S) & Lúcio Lara Santos (IPO)
11:00 – 11:40 Mind the GAGs in gastric cancer
Ana Magalhães, IPATIMUP/i3S University of Porto, Portugal
11:40 – 12:10 Selected talk
Cracking the ErbB2 Sugar Code in Gastric Cancer – A Bittersweet Functional Target
Henrique Duarte, IPATIMUP/i3S University of Porto, Portugal
12:10 – 12:45 Speed talks
Chairs: Rita Matos, i3S & Daniela Freitas, i3S
12:45 – 14:15 Lunch break
Session 2: Glycans in cancer molecular and cell biology
Chairs: Carmen Jerónimo (IPO, ICBAS) & Ana Magalhães (ICBAS/i3S)
KEYNOTE TALK
14:15 – 14:55 Role of Notch Glycosylation in Cancer
Robert Haltiwanger, Complex Carbohydrate Research Center, Georgia, USA
14:55 – 15:25 – Selected talk
GALA: a Glycopathway regulating tissue remodelling
Frédéric Bard, CRCM, France
15:25 – 15:55 – Selected talk
New insights into the role of sialylation in breast cancer immune evasion and immunotherapy resistance
Stefan Mereiter, IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Austria
16:00-16:30 Coffee break
Special Session
Chair: Celso A Reis (i3S)
16:30 – 17:20 Galectins: novel glycocheckpoints and therapeutic targets in cancer
Gabriel Rabinovich, Instituto de Biología y Medicina Experimental, CONICET and University of Buenos Aires, Argentina
20:00 Meeting Dinner
Session 3: Glycosylation in tumor microenvironment and immune modulation
Chairs: Maria Oliveira (i3S) & Joana Gomes (i3S)
KEYNOTE TALK
9:00 – 9:40 Cell surface heparan sulfate as a multifunctional modulator and therapeutic target of breast cancer progression
Martin Götte, University of Münster, Germany
KEYNOTE TALK
9:40 – 10:30 Targeting cancer-associated sialylation for cancer immunotherapy
Heinz Läubli, University Hospital Basel, Switzerland
10:30 – 11:00 Coffee break
11:00 – 11:30 Selected talk
Glycoproteogenomics Characterization of the CD44 Splicing Code in Bladder Cancer Towards Precision Oncology
José Alexandre Ferreira, IPO-Porto, Portugal
11:30 – 12:00 Selected talk
Monensin disrupts the synthesis of SLeX in tumors and influences its malignant features
Catarina Gomes, i3S/ IPATIMUP, Portugal
12:00 – 12:40 Speed talks
Chairs: Rita Matos, i3S & Filipe Pinto, i3S
12:40 – 14:15 Lunch break
Session 4: Translational Research and glycan-based clinical applications
Chairs: Salomé Pinho (i3S) & Júlio Oliveira (IPOP)
KEYNOTE TALK
14:15 – 14:55 Glycoimmunology: sugars on the fuss for improved immunotherapies?
Paula Videira, Glycoimmunology Group, Nova University Lisbon, Portugal & CellmAbs Biopharmaceuticals
14:55– 15:25 Selected talk
Glycomimetics as next generation of precision therapeutics in cancer: the discovery of Fucosyltransferase-Specific Inhibition
Barbara Richichi, Department of Chemistry ‘Ugo Schiff’, University of Florence, Italy
15:25 – 15:40 Closing session
Chair: Celso A Reis & André Albergaria (i3S)
