Stemness & Metastasis: Advances in Research and Clinical Translation
20-21 May 2021

Chris D. Madsen

Department of Laboratory Medicine, Division of Translational Cancer Research, Lund University, Lund, Sweden

The research group of Chris D. Madsen aims to understand single cell behaviour and remodelling of the extracellular matrix (ECM) taking place during the progression of cancer. His work is focusing on obstructing metastatic spread of cancer, by targeting the individual cancer cells and by rewiring the stromal compartment of tumour microenvironment. His research also aims at improving drug delivery -and efficacy, by interfering and rewiring the tumour microenvironment.

Chris D. Madsen is a leading expert on 3D high-resolution imaging of the ECM1, and an expert in the fields of cancer metastasis, tumour microenvironment, tissue stiffness and mechano-biology. His laboratory routinely conducts preclinical animal experiments, often in conjunction with intravital imaging modalities such as multi-photon microscopy, second harmonic generation (SHG) imaging and multispectral optoacoustic tomography (MSOT).