PROGRAMME PORTO-BORDEAUX MEETING

PROGRAMME PORTO-BORDEAUX MEETING

8.15 Registration

Opening Session

8.45 Welcome Session
Béatrice Vergier, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Jean-Philippe Merlio, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Manuel Sobrinho Simões, i3S/IPATIMUP & Faculty of Medicine of the University of Porto & CHUSJ
Rui Henrique, Portuguese Oncology Institute of Porto & ICBAS

Session I – The Cancer Ecosystem: applications in pathology
(Chair: Fátima Carneiro)

9.00  Tumour infiltrating lymphocytes and PD-L1 in breast carcinomas
(Fernando Schmitt)

9.20 Clinical, histological and molecular predictors of metastatic melanoma responses to anti-PD-1 immunotherapy
(M. Darmon and B. Vergier)

9.40 Impact of STK11/LKB1 tumour suppressor gene mutations on the response of bronchopulmonary carcinomas to immunotherapy
(H. Bégueret and D. Cappelen)

10.00  The microbiome and gastric cancer: beyond Helicobacter pylori
(Céu Figueiredo) 

10:20 Coffee break

Session II – The Cancer Ecosystem: perspectives in pathology research
(Chair: Leonor David)

10:40  DICER1 germline alterations in papillary thyroid carcinoma cases from TCGA database
(Sule Canberk)

11:00 Proteomic profiling of liver CK7+/CK20- (A)DKs on FFPE blocks: primary versus metastatic?
(C. Laffon, A.A. Raymond and B. Le Bail)

11:20 The “genvironment” and the major role of epigenetics in human germ cell tumours: looking for disease biomarkers and novel treatment options
(João Lobo) 

11:40 Uterine and vaginal sarcomas resembling fibrosarcoma: a clinicopathological and molecular analysis of 13 cases showing common NTRK-rearrangements and the description of a COL1A1-PDGFB fusion novel to uterine neoplasms
(S. Croce)

Session III – Hot topics in pathology: Battle of controversies
(Chair: Catarina Eloy)

12:00  Is p16 a decisive surrogate marker to diagnose HPV related carcinomas?
Con: Carla Bartosch
Pros: José Manuel Lopes

12:25  Is NGS necessary to assess mutations (or is FISH still necessary)?
Con: José Carlos Machado
Pros: Jean-Philippe Merlio

12:50 Lunch break

Session IV – Interactive Cyto-histologic Slide Seminar – Part I
(Chair: Manuel Sobrinho Simões)

14:00-14:45   Case 1 to 4  

15:00 Coffee break

Session IV – Interactive Cyto-histologic Slide Seminar – Part II
(Chair: Mariana Afonso)

15:30-16:15   Case 5 to 8

Special Pathology Session
(Chair: Rui Henrique)

16:30 The funny stories behind the CVs: Pathology beyond the microscope
Jean-Philippe Merlio,CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn

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8.15 Registration

Opening Session

8.45 Welcome Session
Béatrice Vergier, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Jean-Philippe Merlio, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Manuel Sobrinho Simões, i3S/IPATIMUP & Faculty of Medicine of the University of Porto & CHUSJ
Rui Henrique, Portuguese Oncology Institute of Porto & ICBAS

Session I – The Cancer Ecosystem: applications in pathology
(Chair: Fátima Carneiro)

9.00  Tumour infiltrating lymphocytes and PD-L1 in breast carcinomas
(Fernando Schmitt)

9.20 Clinical, histological and molecular predictors of metastatic melanoma responses to anti-PD-1 immunotherapy
(M. Darmon and B. Vergier)

9.40 Impact of STK11/LKB1 tumour suppressor gene mutations on the response of bronchopulmonary carcinomas to immunotherapy
(H. Bégueret and D. Cappelen)

10.00  The microbiome and gastric cancer: beyond Helicobacter pylori
(Céu Figueiredo) 

10:20 Coffee break

Session II – The Cancer Ecosystem: perspectives in pathology research
(Chair: Leonor David)

10:40  DICER1 germline alterations in papillary thyroid carcinoma cases from TCGA database
(Sule Canberk)

11:00 Proteomic profiling of liver CK7+/CK20- (A)DKs on FFPE blocks: primary versus metastatic?
(C. Laffon, A.A. Raymond and B. Le Bail)

11:20 The “genvironment” and the major role of epigenetics in human germ cell tumours: looking for disease biomarkers and novel treatment options
(João Lobo) 

11:40 Uterine and vaginal sarcomas resembling fibrosarcoma: a clinicopathological and molecular analysis of 13 cases showing common NTRK-rearrangements and the description of a COL1A1-PDGFB fusion novel to uterine neoplasms
(S. Croce)

Session III – Hot topics in pathology: Battle of controversies
(Chair: Catarina Eloy)

12:00  Is p16 a decisive surrogate marker to diagnose HPV related carcinomas?
Con: Carla Bartosch
Pros: José Manuel Lopes

12:25  Is NGS necessary to assess mutations (or is FISH still necessary)?
Con: José Carlos Machado
Pros: Jean-Philippe Merlio

12:50 Lunch break

Session IV – Interactive Cyto-histologic Slide Seminar – Part I
(Chair: Manuel Sobrinho Simões)

14:00-14:45   Case 1 to 4  

15:00 Coffee break

Session IV – Interactive Cyto-histologic Slide Seminar – Part II
(Chair: Mariana Afonso)

15:30-16:15   Case 5 to 8

Special Pathology Session
(Chair: Rui Henrique)

16:30 The funny stories behind the CVs: Pathology beyond the microscope
Jean-Philippe Merlio,CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn

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