11 May 2017
09:00 Welcome Session
Manuel Sobrinho-Simões, i3S – Ipatimup
Mário Barbosa, i3S
Session 1: Liquid biopsies: the basics
Chairs: Raquel Seruca (i3S-Ipatimup) and Carmen Jerónimo (IPO-Porto)
09:30 Liquid biopsies: our path from bench to clinical management of cancer patients
José Luís Costa, i3S – Ipatimup
10:00 Structures, origins and functions of circulating DNA and move towards application in oncology
Alain R. Thierry, Inserm, Université des Sciences de Montpellier, France
10:30 Coffee break
Chairs: Rui Henrique (IPO-Porto) and José Luís Costa (i3S-Ipatimup)
11:00 Exploiting the Biology of Exosomes for Diagnosis and Treatment of Pancreatic Cancer
Raghu Kalluri, The University of Texas MD Anderson Cancer Center, USA
11:30 The use of circulating tumor cells (CTC) as a liquid biopsy tool in cancer research
Harriet Wikman, Institute of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany
12:30 Lunch (lobby of Corino de Andrade Auditorium)
13:45 Posters Speed-talks Session (1st Floor – Room A)
Session 2: Technology for liquid biopsies
Chairs: José Carlos Machado (i3S-Ipatimup) and Fernando Schmitt (i3S-Ipatimup)
15:00 Droplet-based digital PCR for cancer research
Valerie Taly, CNRS Research Director / Université Paris Descartes, France
15:30 Cancer Biomarker Detection
Goreti Sales, BioMark, Sensor Research ISEP, Porto, Portugal
16:00 Coffee break
Session 3: Liquid Biopsy: the perspective from health industry
Chairs: Júlio Oliveira (IPO-Porto) and André Albergaria (i3S-Ipatimup)
16:30 DNA Sequencing of Clinical Plasma Samples to Identify Markers of Response and Resistance in Cancer Patients
Brian Dougherty, AstraZeneca Oncology IMED Translational Science Group, USA
17:00 Developments in tools for Oncology testing from Ion Torrent
Andy Felton, ThermoFisher, USA
20:00 Meeting Dinner: Cruise on the Douro river and dinner aboard.
12 May 2017
Session 4: Liquid biopsies clinical applications
Chairs: Venceslau Hespanhol (Centro Hospitalar de S. João) and Luís Costa (Lisbon University, Hospital de Santa Maria)
09:00 AR-V7 as a biomarker and therapeutic target for advanced prostate cancer
Emmanuel Antonarakis, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, USA
09:30 Cancer evolution as a therapeutic target
Alberto Bardelli, Candiolo Cancer Institute IRCCS / University of Torino, Italy
10:00 Coffee break
Chairs: Fátima Carneiro (Centro Hospitalar de S. João) and Nuno Sousa (IPO-Porto)
10:30 Liquid Biopsies in Clinical Oncology: how many dimensions and how much dynamics?
Luís Costa, Lisbon University / Hospital de Santa Maria, Portugal
11:00 EGFR plasma testing in Lung Cancer – practical experience
Shobhit Baijal, Heartlands Hospital Birmingham, UK / Phillipe Taniere, Queen Elizabeth Hospital / Birmingham Medical School , UK
12:00 Lunch (lobby of Corino de Andrade Auditorium)
13:45 Posters Speed-talks Session (1st Floor – Room A)
Session 5: Implementation of liquid biopsies for precision medicine
Chairs: Celso Reis (i3S-Ipatimup) and Ana Castro (Centro Hospitalar do Porto)
15:00 New Horizons for Improvements in outcome or patients with Small Cell Lung Cancer
Caroline Dive, Cancer Research UK Manchester Institute, UK
15:30 From Research to Routine: a snapshot into the clinical use of Liquid Biopsy in Molecular Diagnostics
Luca Quagliata, Universitätsspital Basel, Switzerland
16:00 Closing
