Department of Biology, School of Arts & Sciences, University of Pennsylvania, Philadelphia, USA
Dr. Wei Guo is a Professor at the University of Pennsylvania Department of Biology. His laboratory has long-standing interest in the molecular basis and regulatory mechanisms of vesicular trafficking and tumor cell invasion. He has applied the basic cell biological principles to the understanding of cancer, especially melanoma. Taking a multidisciplinary approach that combines biochemistry, biophysics, genetics, and advanced microscopic imaging, his laboratory has made fundamental discoveries that contributed to the molecular understanding of cancer metastasis, melanoma drug resistance, and more recently tumor immune evasion.