Department of Medicine 5 –- Hematology and Clinical Oncology, University of Erlangen, Erlangen, Germany
Dimitrios Mougiakakos is the department’s managing attending and professor for tumor immunology. His has a long standing interest in tumor immunology, performed his postdoctoral training at the Karolinska Institutet, and subsequently established his own independent research group for “Translational Tumor- and Transplantation Immunology” at the University of Erlangen-Nuremberg. His group studies the immune system in cancer and following stem cell transplantation while focusing on immunometabolism.
Tumors can impact immune responses and thereby escape from immunosurveillance. A better understanding of the underlying mechanisms shall help us to develop innovative immune-based therapies against cancer. Furthermore, we seek out to utilize our insights from tumor biology for a targeted immunological fine-tuning. Those approaches could represent the foundation for novel experimental interventions against Graft-versus-Host disease that affects transplanted patients and that can be difficult treat.