27th PORTO CANCER MEETING
Stemness & Metastasis: Advances in Research and Clinical Translation
7-8 MAY 2020

Toni Celià-Terrassa

Cancer Stem Cells & Metastasis Lab, Hospital del Mar Medical Research Institute (IMIM), Barcelona Biomedical Research Park (PRBB), Spain

Toni Celià-Terrassa is a junior group leader of the Cancer Stem Cells & Metastasis Lab at the Hospital del Mar Medical Research Institute (IMIM), Barcelona. In 2018, he obtained the Miguel Servet Grant to become an independent investigator and was incorporated at the IMIM Cancer Program. During the past years, his research has been focused on studying the cancer cell properties required for metastasis. He obtained his PhD by the University of Barcelona in 2012, and his thesis unveiled new implications of the reversable epithelial-to-mesenchymal transition (EMT) and stemness during the metastatic colonization. In 2012, he moved to Princeton (NJ, USA) where he was a Postdoctoral Fellow at Dr. Yibin Kang´s Lab; Princeton University (2012-2017). There, he specialized in breast cancer metastasis and stem cells. He elucidated the intricate molecular mechanisms of normal and malignant mammary stem cells to shield from immune system signals in breast cancer. In addition, he also studied the spatiotemporal dynamics of EMT and MET generating distinct metastatic-gene programs. In summary, he has done remarkable contributions to the mammary stem cell field, the cancer stem cell, and the metastasis colonization research. Today his group is specialized on understanding the implications the EMT dynamics at the distant site of metastasis and the tumor-immune interplay during the metastatic colonization.