26th Porto Cancer Meeting 2019
The Cancer Ecosystem: From Research to Pathology and Treatment
& 5th Joint Meeting Porto-Bordeaux 2019
The Cancer Ecosystem:
from Research to Pathology & Treatment
02 MAY 2019
09.00 Welcome Session, Manuel Sobrinho-Simões, i3S/ Ipatimup & Mário Barbosa, i3S
Session 1: Microbiome in Cancer
Chairs: Fátima Carneiro, CHSJ and Céu Figueiredo, i3S
9.15-9.45 Role of the gut microbiome in causing, detecting and treating colorectal cancer
Paul O’Toole, School of Microbiology, University College Cork, Ireland
9.45-10.15 Interplay between immune contexture and gut microbiota in human colorectal cancer
Giandomenica Iezzi, Ente Ospedaliero Cantonale and Università della Svizzera Italiana, Switzerland
10.15-10.45 Coffee-break
10.45-11.15 Gut microbiota, can we improve the outcome of cancer immunotherapy
Meriem Messaoudene, Centre de Recherche du Centre Hospitalier de l’Universite de Montreal, Canada
11.15-11.30 SELECTED TALK: Gastric cancer is characterized by a dysbiotic microbiome
Rui Ferreira, i3S – Instituto de Investigação e Inovação em Saúde/ Ipatimup, Portugal
SPECIAL SESSION: A tribute to socitey
Chair: José Carlos Machado, i3S
11.30-12.00 How the contributions from society have improved the clinical management and molecular understanding of paediatric brain tumours
Jorge Lima, i3S – Instituto de Investigação e Inovação em Saúde, Portugal &
Maria João Gil da Costa, Department of Paediatric Oncology, Centro Hospitalar de São João, Portugal
12.00-13.00 Lunch
13.00-14.30 Speed Talks | Auditorium Corino de Andrade
Chairs: Patrícia Oliveira, i3S and Hugo Caires, i3S
Session 2: Tumour Microenvironment
Chairs: Rui Henrique, IPO-Porto and Raquel Seruca, i3S
14.30-15.00 The crosstalk between stem-like cancer cells and the tumor microenvironment
Joana Paredes, i3S – Instituto de Inovação em Saúde / Ipatimup, Portugal
15.00-15.30 Metabolic interactions in chronic lymphocytic leukemia
Dimitrios Mougiakakos, Department of Medicine 5 – Hematology and Clinical Oncology, University of Erlangen, Germany
15.30-16.00 Coffee-break
16.00-16.30 Neoadjuvant chemotherapy elicits a pro-metastatic cascade through extracellular vesicles
Ioanna Keklikoglou, Swiss Institute for Experimental Cancer Research, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Switzerland
16.30-16.45 SELECTED TALK: Pancreatic Cancer Stem Cells Coordinate an Organized Exosomes Communication Network that Dysregulates the Hippo Pathway Contributing to Pancreatic Cancer Progression
Carolina Ruivo, i3S – Instituto de Investigação e Inovação em Saúde and Instituto de Ciências Biomédicas de Abel Salazar, Portugal
20.00 Meeting Dinner
03 MAY 2019
Session 3: Inflammation and Cancer
Chairs: Guilherme Macedo, CHSJ and José Carlos Machado, i3S
9.00-9.30 “Inflammation and homeostasis” to understand “Inflammation and cancer”
Francisco Real, Spanish National Cancer Research Centre / Universitat Pompeu Fabra, Spain
09.30-10.00Immune-metabolism in Liver Cancer and Cancer Cachexia
Erwin Wagner, Medical University Vienna, Austria
10.00-10.30 Coffee Break
10.30-11.00 On the role of innate and adaptive immune cells in fatty liver disease and subsequent liver cancer
Mathias Heikenwälder,Chronic Inflammation and Cancer, German Cancer Research Center, Heidelberg, Germany
11.00-11.15 SELECTED TALK: Crosstalk of signaling hubs and chronic inflammation in human tumorigenesis
Carla Lopes, Instituto Gulbenkian de Ciência, Portugal
11.15-12.30 Speed Talks | Auditorium Corino de Andrade
Chairs: Sérgia Velho, i3S and Stefan Mereiter, i3S
12.30-14.00 Lunch and Poster viewing
Session 4: Immunotherapy
Chairs: Júlio Oliveira, IPO-Porto and Sónia Melo, i3S
14.00-14.30 The Exosomes in Immune Suppression and Tumor Progression
Wei Guo, Department of Biology, School of Arts & Sciences, University of Pennsylvania, USA
14.30-15.00 Neoadjuvant immunotherapy – the pathway to biomarker identification and personalized therapy
Christian Blank, Netherlands Cancer Institute, the Netherlands
15.00-15.30 Coffee-break
16.00-16.30 Signal Finding Platform trials: optimizing drug development
Pablo Martinez Rodriguez, Medimmune, LLC, USA
16.30-16.45 SELECTED TALK: Homologous recombination deficiency in metastatic gastric cancer
Nuno Sousa, IPO-Porto, Portugal
Adjourn