PROGRAMME PORTO-BORDEAUX MEETING

01 MAY 2019

 

8.15 Registration

Opening Session

8.45 Welcome Session
Béatrice Vergier, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Jean-Philippe Merlio, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Manuel Sobrinho Simões, i3S/IPATIMUP & Faculty of Medicine of the University of Porto & CHUSJ
Rui Henrique, Portuguese Oncology Institute of Porto & ICBAS

Session I – The Cancer Ecosystem: applications in pathology
(Chair: Fátima Carneiro)

9.00  Tumour infiltrating lymphocytes and PD-L1 in breast carcinomas
(Fernando Schmitt)

9.20 Clinical, histological and molecular predictors of metastatic melanoma responses to anti-PD-1 immunotherapy
(M. Darmon and B. Vergier)

9.40 Impact of STK11/LKB1 tumour suppressor gene mutations on the response of bronchopulmonary carcinomas to immunotherapy
(H. Bégueret and D. Cappelen)

10.00  The microbiome and gastric cancer: beyond Helicobacter pylori
(Céu Figueiredo)
 

10:20 Coffee break

Session II – The Cancer Ecosystem: perspectives in pathology research
(Chair: Leonor David)

10:40  DICER1 germline alterations in papillary thyroid carcinoma cases from TCGA database
(Sule Canberk)

11:00 Proteomic profiling of liver CK7+/CK20- (A)DKs on FFPE blocks: primary versus metastatic?
(C. Laffon, A.A. Raymond and B. Le Bail)

11:20 The “genvironment” and the major role of epigenetics in human germ cell tumours: looking for disease biomarkers and novel treatment options
(João Lobo) 

11:40 Uterine and vaginal sarcomas resembling fibrosarcoma: a clinicopathological and molecular analysis of 13 cases showing common NTRK-rearrangements and the description of a COL1A1-PDGFB fusion novel to uterine neoplasms
(S. Croce)

Session III – Hot topics in pathology: Battle of controversies
(Chair: Catarina Eloy)

12:00  Is p16 a decisive surrogate marker to diagnose HPV related carcinomas?
Con: Carla Bartosch
Pros: José Manuel Lopes

12:25  Is NGS necessary to assess mutations (or is FISH still necessary)?
Con: José Carlos Machado
Pros: Jean-Philippe Merlio

12:50 Lunch break

Session IV – Interactive Cyto-histologic Slide Seminar – Part I
(Chair: Manuel Sobrinho Simões)

14:00-14:45   Case 1 to 4  

15:00 Coffee break

Session IV – Interactive Cyto-histologic Slide Seminar – Part II
(Chair: Mariana Afonso)

15:30-16:15   Case 5 to 8

Special Pathology Session
(Chair: Rui Henrique)

16:30 The funny stories behind the CVs: Pathology beyond the microscope
Jean-Philippe Merlio,CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn


Organizing Committee

Bordeaux Team

BELLEANNÉE Geneviève, CHU Bordeaux
CAPPELLEN David, CHU and Inserm U1053
CROCE Sabrina, Bergonié Institute and Inserm U1218
LE-BAIL Brigitte, CHU Bordeaux and Inserm U1053
MERLIO Jean-Philippe, CHU Bordeaux and Inserm U1053
VERGIER Béatrice, CHU Bordeaux and Inserm U1053

Porto Team

Manuel Sobrinho Simões, i3S/IPATIMUP & CHUSJ & FMUP
Fátima Carneiro, i3S/IPATIMUP & CHUSJ & FMUP
Carla Bartosch, IPO & ICBAS
Elisabete Rios, i3S/IPATIMUP & CHUSJ & FMUP
António Polónia, i3S/IPATIMUP
Catarina Costa, CHUSJ & FMUP
Tiago Costa Pereira, CHUSJ

 

01 MAY 2019

 

8.15 Registration

Opening Session

8.45 Welcome Session
Béatrice Vergier, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Jean-Philippe Merlio, CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn
Manuel Sobrinho Simões, i3S/IPATIMUP & Faculty of Medicine of the University of Porto & CHUSJ
Rui Henrique, Portuguese Oncology Institute of Porto & ICBAS

Session I – The Cancer Ecosystem: applications in pathology
(Chair: Fátima Carneiro)

9.00  Tumour infiltrating lymphocytes and PD-L1 in breast carcinomas
(Fernando Schmitt)

9.20 Clinical, histological and molecular predictors of metastatic melanoma responses to anti-PD-1 immunotherapy
(M. Darmon and B. Vergier)

9.40 Impact of STK11/LKB1 tumour suppressor gene mutations on the response of bronchopulmonary carcinomas to immunotherapy
(H. Bégueret and D. Cappelen)

10.00  The microbiome and gastric cancer: beyond Helicobacter pylori
(Céu Figueiredo)
 

10:20 Coffee break

Session II – The Cancer Ecosystem: perspectives in pathology research
(Chair: Leonor David)

10:40  DICER1 germline alterations in papillary thyroid carcinoma cases from TCGA database
(Sule Canberk)

11:00 Proteomic profiling of liver CK7+/CK20- (A)DKs on FFPE blocks: primary versus metastatic?
(C. Laffon, A.A. Raymond and B. Le Bail)

11:20 The “genvironment” and the major role of epigenetics in human germ cell tumours: looking for disease biomarkers and novel treatment options
(João Lobo) 

11:40 Uterine and vaginal sarcomas resembling fibrosarcoma: a clinicopathological and molecular analysis of 13 cases showing common NTRK-rearrangements and the description of a COL1A1-PDGFB fusion novel to uterine neoplasms
(S. Croce)

Session III – Hot topics in pathology: Battle of controversies
(Chair: Catarina Eloy)

12:00  Is p16 a decisive surrogate marker to diagnose HPV related carcinomas?
Con: Carla Bartosch
Pros: José Manuel Lopes

12:25  Is NGS necessary to assess mutations (or is FISH still necessary)?
Con: José Carlos Machado
Pros: Jean-Philippe Merlio

12:50 Lunch break

Session IV – Interactive Cyto-histologic Slide Seminar – Part I
(Chair: Manuel Sobrinho Simões)

14:00-14:45   Case 1 to 4  

15:00 Coffee break

Session IV – Interactive Cyto-histologic Slide Seminar – Part II
(Chair: Mariana Afonso)

15:30-16:15   Case 5 to 8

Special Pathology Session
(Chair: Rui Henrique)

16:30 The funny stories behind the CVs: Pathology beyond the microscope
Jean-Philippe Merlio,CHU Bordeaux and Bordeaux University, Inserm U1053 BaRITOn


Organizing Committee

Bordeaux Team

BELLEANNÉE Geneviève, CHU Bordeaux
CAPPELLEN David, CHU and Inserm U1053
CROCE Sabrina, Bergonié Institute and Inserm U1218
LE-BAIL Brigitte, CHU Bordeaux and Inserm U1053
MERLIO Jean-Philippe, CHU Bordeaux and Inserm U1053
VERGIER Béatrice, CHU Bordeaux and Inserm U1053

Porto Team

Manuel Sobrinho Simões, i3S/IPATIMUP & CHUSJ & FMUP
Fátima Carneiro, i3S/IPATIMUP & CHUSJ & FMUP
Carla Bartosch, IPO & ICBAS
Elisabete Rios, i3S/IPATIMUP & CHUSJ & FMUP
António Polónia, i3S/IPATIMUP
Catarina Costa, CHUSJ & FMUP
Tiago Costa Pereira, CHUSJ